The pharmacological management of mania

by Dr Karine A.N. Macritchie and Professor Allan H. Young


Published: July 2012


The pharmacological management of maniaIn the management of mania, pharmacological treatment plays a key part in any comprehensive package of care. The pharmacological management of mania is a skill essential to the practice of acute general psychiatry.


Over recent years, new agents have joined the armoury of anti-manic treatments and the evidence base for these treatments is increasing. Updated guidelines for evidence-based treatments for mania have been published; however, the management of treatment-resistant mania remains challenging and is informed by few studies.


This module summarises current thinking on the neural mechanisms of mania and the current view of best practice in its pharmacological management, focusing particularly on recently published guidelines from the British Association for Psychopharmacology. 


  • The assessment of mania and its context will be discussed.


  • A very brief overview of the neurophysiology of mood regulation and the role of anti-manic agents will follow.


  • Thereafter, the recent British Association for Psychopharmacology guidelines for the management of mania and maintenance treatment will be outlined. Strategies for treatment resistant mania will also be discussed.


Start the module



If you like this module, you may also be interested in:


The pharmacological treatment of resistant depression – an overview

by Professor Philip J. Cowen


The pharmacological management of anxiety disorders by Dr Zia Nadeem and Dr Allan Scott 


Rapid tranquillisation of the acutely disturbed patient by Dr Stephen Pereira, Dr Deepak Garg and Dr David Branford



BJPsych Advances: related articles for CPD Online



Related Advances articles


Download take-home notes to print and annotateDownload take-home notes to print and annotate


© 2015 Royal College of Psychiatrists