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Module introduction

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Section 1: The basics

(1.1) Section 1: The basics

(1.2) Some basic definitions

(1.3) The importance of genotype-phenotype correlation

(1.4) Nature or nurture?

(1.5) Why is finding susceptibility genes important?

(1.6) Why is finding susceptibility genes important?

(1.7) Why is finding susceptibility genes important?

(1.8) Why is finding susceptibility genes important?

(1.9) Section 1: Recap

(1.10) Section 1: Summary

Section 2: Finding genes for mental illness

(2.1) Section 2: Finding genes for mental illness

(2.2) Three questions

(2.3) Does the disorder have an important genetic contribution?

(2.4) Does the disorder have an important genetic contribution?

(2.5) Does the disorder have an important genetic contribution?

(2.6) Does the disorder have an important genetic contribution?

(2.7) In what region of the genome might a susceptibility gene be located?

(2.8) Linkage regions for schizophrenia

(2.9) Candidate genes

(2.10) Association studies

(2.11) Association studies

(2.12) Association studies

(2.13) Association studies

(2.14) Risk genes for schizophrenia (at last)

(2.15) Chromosomal analysis

(2.16) The DISC1 story

(2.17) The DISC1 story

(2.18) The DISC1 story

(2.19) Copy number variations (CNVs)

(2.20) Copy number variations (CNVs)

(2.21) Section 2: Recap

(2.22) Section 2: Summary

Section 3: What happens next?

(3.1) Section 3: What happens next?

(3.2) The Human Genome Project

(3.3) The HapMap

(3.4) Bioinformatics

(3.5) Proteins and susceptibility

(3.6) Recent technical advances

(3.7) Recent technical advances

(3.8) Recent technical advances

(3.9) Implications for future research

(3.10) Section 3: Recap

(3.11) Section 3: Summary

Section 4: Genetics research and clinical psychiatry

(4.1) Section 4: Genetics research and clinical psychiatry

(4.2) Current psychiatric treatments

(4.3) New treatments based on understanding pathogenesis

(4.4) How can genetics improve our classification of mental illness?

(4.5) Figure 9: Models of the possible genetic relationships between schizophrenia and bipolar disorder

(4.6) Gene-environment interplay: stress and the serotonin transporter

(4.7) Pharmacogenomics

(4.8) Social and ethical issues

(4.9) Use of genetic information

(4.10) Section 4: Recap

(4.11) Section 4: Summary

Module summary

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